Biomedical Device Laboratory
It is technically difficult to acquire large-field images under the complexity and cost restrictions of a diagnostic and instant field research purpose. The goal of the introduced large-field imaging system is to achieve a tolerable resolution for detecting microscale particles or objects in the entire image field without the field-curvature effect while maintaining a cost-effective procedure and simple design. Herein, we propose a wide field-of-view (FOV) fluorescence imaging method with an unconventional optical-quality curved sample chamber that corrects the field curvature caused by a simple lens. Hence, a wide FOV imaging system with the proposed curved sample chamber would enable us to acquire an undistorted image of a large sample volume without requiring a time-consuming scanning process in poin-of-care diagnostic apllications.